FFWD tip: Around 24:00 they finally start in on cosmological fine tuning.
Nicholas Beale (http://www.questionsoftruth.org/) makes the argument that because the constants of physics fall within a small range allowing for complex life, we can safely assume that our universe exists by for a reason, that is, by design. Incidentally, Beale is given almost ten minutes to lecture with only minor questioning from the host. To my knowledge, this has never happened to a guest sceptic.
Julian Baggini (http://julianbaggini.blogspot.com/) makes the case that it is a bad idea for theists to plug God into the epistemic gaps which science has yet to explain, because much of the time science comes along later on and fills those gaps with solid scientific theories. He says that it is a bad idea to leave religion vulnerable to scientific disproof in this way.
p.s. Big W00t 4 STAR TREK music!